Prof. Dr. Helmut Sies
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Dr. Helmut Sies is known as a Redox Pioneer for his transformative contributions to the field of redox biology. His illustrious career spans decades, marked by groundbreaking research that has reshaped our understanding of oxidative stress and cellular metabolism. Dr. Sies’s pioneering work includes identifying hydrogen peroxide (H2O2) as a crucial aerobic metabolite and developing innovative methods for quantifying cellular H2O2 levels. He has elucidated the roles of central redox systems, such as NAD, NADP, and the antioxidant glutathione (GSH), across various subcellular compartments. Notably, his research led to the discovery of ebselen, a selenoorganic compound with significant implications as a glutathione peroxidase mimic. With over 600 articles and 28 edited books to his name, Dr. Sies’s impact on the scientific community is profound. His pioneering insights into oxidative stress and the health benefits of dietary compounds like carotenoids and flavonoids continue to inspire researchers worldwide, shaping the landscape of modern redox biology.